Dejan Lovren joined Philippe Coutinho in suffering an apparent hamstring injury at the Britannia Stadium, increasing the Reds's significant numbers on the sidelines
Coutinho was forced off after just 18 minutes after seemingly hurting his hamstring when delivering a ball into the box before Lovren was forced off with a similar issue 15 minutes later following a sliding tackle.
The Croatia international was replaced by James Milner, who himself has only just returned from injury, with Lucas Leiva retreating into defence.
Liverpool are currently without Danny Ings and Joe Gomez due to long-term injuries, while Divock Origi, Martin Skrtel and Jordan Rossiter are expected to be sidelined for a number of weeks.
Daniel Sturridge and Jordan Henderson have both returned to the first team but since suffered setbacks, while Jon Flanagan is building up his fitness after a serious knee injury.